Gender Preselection

We now offer gender preselection as part of a multi-center clinical research trial.  Gender preselection is for patients who want to increase the chance of having a child of a desired sex for the prevention of sex-linked diseases or for family balancing.  Because it is the sperm cell that carries the X (girl) or Y (boy) chromosome, semen can be sorted into X- or Y-enriched samples to increase the probability of having a child of the desired sex. A semen sample typically contains approximately 50% X- and 50% Y-bearing sperm.
XSORT®
The current separation technology enriches the XSORT® to increase the probability of conceiving a girl has resulted in an average of 88% X-bearing (female) sperm in the enriched specimen and 91% of the babies have been female.

YSORT®
The current separation technology enriches the YSORT® to increase the probability of conceiving a boy has resulted in an average of 73% Y-bearing (male) sperm in the enriched specimen and 76% of the babies have been male.

Conception Rate
The MicroSort Clinic average cumulative IUI clinical pregnancy rate is 16.6% (242/1452) per treatment cycle. The overall IVF/ICSI clinical pregnancy rate is 33% (164/497) This includes MicroSort collaborators doing IVF/ICSI.

Pregnancies & Births
As of January 2004, more than 500 pregnancies have been achieved using MicroSort®; 419 babies have been born so far with many more due to deliver.

Men can collect a semen sample here at the Reproductive Science Institute, where it is frozen and then sent to a laboratory for sperm sorting.  Next the X- or Y- enriched samples are refrozen and then sent back to the Institute, where it can be used for assisted reproductive technology procedures such as IVF or ICSI.

To qualify for gender preselection, you must be married and have at least one child with your spouse.  The husband and wife would need to have blood tests to be sure they are negative for HIV, Hepatitis B or C.  The wife must be 18-39 years of age.

To qualify for the prevention of a sex-linked disease, you must be married, and be a known carrier of sex-linked or sex-limited disorder.  The husband and wife would need to have blood tests to be sure they are negative for HIV, Hepatitis B or C.




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